The Palace of the Grand Dukes of Lithuania is a historical palace complex located in the Old Town of Vilnius, Lithuania. The original palace was built in the 15th century for the Grand Duke of Lithuania, and it was the political, cultural and administrative center of the country for centuries.

The palace underwent several expansions and renovations over the centuries, and it was partially destroyed during World War II. It was reconstructed in the early 21st century and opened to the public as a museum in 2018.

The palace complex consists of several buildings, including the Gothic Palace, the Renaissance Palace, and the Palace of the Grand Dukes, which was built in the 18th century. The Gothic Palace is the oldest part of the complex and features an exhibition on the history of the palace and Lithuania. The Renaissance Palace houses temporary exhibitions and events, while the Palace of the Grand Dukes contains the restored interiors of the Grand Duke's apartments and a permanent exhibition on the history of Lithuania.

The palace complex also includes a courtyard, a palace chapel, and a tower offering panoramic views of Vilnius. The Palace of the Grand Dukes of Lithuania is an important historical and cultural landmark in Vilnius and a must-visit for anyone interested in the history of Lithuania and the region.